Andean Crossroads

Argentina & Chile in 22 Days

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Embark on an unforgettable 22-day adventure through some of South America's most iconic and breathtaking destinations. This carefully crafted itinerary invites you to explore the diverse landscapes, vibrant cultures, and natural wonders of Argentina and Chile. ­ We begin in Buenos Aires, the passionate and lively capital of Argentina. Discover its European architecture, tango rhythms, and local flavors before heading north to marvel at the majestic Iguazú Falls, a UNESCO World Heritage Site where nature reigns supreme. ­ Next, we travel to the northwest to uncover the rich Andean culture in Salta and Purmamarca. Walk through colonial streets, admire colorful mountain ranges like the Cerro de los Siete Colores, and experience authentic local traditions. ­ Crossing the Andes, we arrive in San Pedro de Atacama, in northern Chile. From salt flats and geysers to star-studded skies, this high-altitude desert offers otherworldly beauty and a deep connection to ancestral lands. ­ After a short flight, enjoy a cultural contrast in Santiago, Chile’s cosmopolitan capital nestled between the mountains and the sea. Then, continue south to Puerto Natales, gateway to the awe-inspiring Torres del Paine National Park, where dramatic peaks, turquoise lakes, and Patagonian wildlife await. ­ Re-entering Argentina, we visit El Calafate to witness the impressive Perito Moreno Glacier, with the option to sail close to its icy walls or even trek atop it. The journey concludes in the southernmost city of the world, Ushuaia, where the Andes meet the Beagle Channel. Here you’ll explore Tierra del Fuego National Park, navigate through scenic islands, and soak in the raw beauty of the end of the world. ­ A perfect balance of adventure, culture, and natural wonders, this journey promises a deep and meaningful experience of Patagonia and beyond.

Trip Description

Embark on an unforgettable 22-day adventure through some of South America's most iconic and breathtaking destinations. This carefully crafted itinerary invites you to explore the diverse landscapes, vibrant cultures, and natural wonders of Argentina and Chile. ­ We begin in Buenos Aires, the passionate and lively capital of Argentina. Discover its European architecture, tango rhythms, and local flavors before heading north to marvel at the majestic Iguazú Falls, a UNESCO World Heritage Site where nature reigns supreme. ­ Next, we travel to the northwest to uncover the rich Andean culture in Salta and Purmamarca. Walk through colonial streets, admire colorful mountain ranges like the Cerro de los Siete Colores, and experience authentic local traditions. ­ Crossing the Andes, we arrive in San Pedro de Atacama, in northern Chile. From salt flats and geysers to star-studded skies, this high-altitude desert offers otherworldly beauty and a deep connection to ancestral lands. ­ After a short flight, enjoy a cultural contrast in Santiago, Chile’s cosmopolitan capital nestled between the mountains and the sea. Then, continue south to Puerto Natales, gateway to the awe-inspiring Torres del Paine National Park, where dramatic peaks, turquoise lakes, and Patagonian wildlife await. ­ Re-entering Argentina, we visit El Calafate to witness the impressive Perito Moreno Glacier, with the option to sail close to its icy walls or even trek atop it. The journey concludes in the southernmost city of the world, Ushuaia, where the Andes meet the Beagle Channel. Here you’ll explore Tierra del Fuego National Park, navigate through scenic islands, and soak in the raw beauty of the end of the world. ­ A perfect balance of adventure, culture, and natural wonders, this journey promises a deep and meaningful experience of Patagonia and beyond.

Accomodation

*2 night´s accommodation in Hotel Carles in Buenos Aires - Double or single Base *2 night´s accommodation in Hotel Guamini Mision in Puerto Iguazú - Double or single Base *2 night´s accommodation in Hotel Antiguo Convento in Salta - Double or single Base *2 night´s accommodation in Hosteria del Amauta in Purmamarca - Double or single Base *3 night´s accommodation in Hotel La Casa de Don Tomas in San Pedro de Atacama - Double or single Base *3 night´s accommodation in Hotel Ibis Manquehue in Santiago de Chile - Double or single Base *2 night´s accommodation in Hotel Factoria in Puerto Natales - Double or single Base *3 night´s accommodation in Hotel Las Dunas, in El Calafate - Double or single Base *2 night´s accommodation in Hotel Patagonia Jarke in Ushuaia - Double or single Base

Stay program

  • day 1:

    Arrival Buenos Aires

    Arrival Buenos Aires

    Welcome to Buenos Aires! We will pick you up at Buenos Aires Airport and then transfer to the hotel in the city center. The rest of the day is at leisure to visit the city by your own. Lodging in Buenos Aires - Double or Single Base Meals: None

  • day 2:

    Sightseeing in Buenos Aires - Dinner Tango Show

    Today, you will enjoy a fantastic introduction to Buenos Aires: This tour offers the perfect balance between driving and light walking, which will allow us to get a great overview of the city’s most iconic areas and districts in just half of a day, and at the same time have the possibility to get off the vehicle, and walk around and have a deeper understanding of the key locations within Buenos Aires: Plaza de Mayo, La Boca neighborhood, and many other attractions. At night, a transfer will pick you up to enjoy a dinner tango show in one of the most prestigious dance venues of Buenos Aires. Located in the heart of San Telmo, Buenos Aires old quarter, this show features over 30 artists on stage with a live orchestra that will leave you speechless. Entering the building is like traveling back in time: it used to be an old tenement house, and the interior is very well-preserved. Featuring both tango and folklore, La Ventana is one of the most complete shows Buenos Aires has to offer. Then we go back to our accommodation. Lodging in Buenos Aires - Double or Single Base Meals: Breakfast, Dinner

  • day 3:

    Buenos Aires - Iguazú - Visit Brazilian Side of the Falls

    After breakfast, transfer to the airport to board your flight to Puerto Iguazú. Upon arrival, a local guide will be waiting to take you across the border into Brazil to explore one of the most breathtaking natural wonders in South America: the Brazilian side of Iguazu Falls. This side of the park offers panoramic views of the full extension of the falls, allowing you to appreciate their grandeur from different angles. The main trail leads you along a scenic path with multiple viewpoints until you reach the spectacular Devil’s Throat lookout – a dramatic highlight of the visit. Enjoy the surrounding subtropical forest, home to a rich variety of flora and fauna. After the tour, transfer to your hotel in Puerto Iguazú and enjoy the rest of the day at leisure. Lodging in Puerto Iguazu - Double or Single Base Included Meals: Breakfast Please note that the domestic Flight from Buenos Aires (AEP / EZE) to Puerto Iguazú (IGR) is not included in the program. .­ From April 2025, passport holders from the United States, Canada and Australia will need to present an eVisa to visit the Brazilian Side of the Falls, which must be applied for through online. The application process is done completely online and as such, no facilitation is required by any intermediaries.

  • day 4:

    Visit Argentinian Side of the Falls

    Today you will explore the Argentine side of Iguazú National Park, where the experience becomes fully immersive, taking you deep into the heart of the waterfalls. Together with a local guide, you’ll walk along the park’s main circuits: the Upper Trail, the Lower Trail, and the Devil’s Throat walkway — each offering striking views and different angles of this natural wonder. The day begins with a ride on the ecological jungle train, which takes you through the lush subtropical forest to the starting point of the Devil’s Throat trail. Along the walkways, you'll be surrounded by jungle and waterfalls, getting incredibly close to the rushing water. For those who are feeling adventurous, there is the possibility to join the “Gran Aventura”, a thrilling experience that combines a 4x4 ride through the forest with a boat trip on the lower Iguazú River, ending with a heart-pounding approach to the base of the falls — a moment where you’re guaranteed to get soaked and exhilarated. This is a full day of nature, wonder, and discovery in one of the most iconic destinations in South America. Lodging in Puerto Iguazu - Double or Single Base Included Meals: Breakfast Optional Excursion Recommended: "The Great Adventure" — Safari Boat Trip

  • day 5:

    Iguazu - Salta

    At the indicated time, we will transfer to Puerto Iguazú Airport to board our flight to the next destination: Salta, located in the northwest region of Argentina. Upon arrival, transfer to the hotel and check-in. The rest of the day is free to explore the city at your own pace. We recommend visiting Cerro San Bernardo, which offers stunning panoramic views of Salta and its surrounding valleys — a perfect spot to get a first impression of this charming colonial city. Lodging in Salta - Double or Single Base Included Meals: Breakfast Please note that the domestic Flight from Puerto Iguazú (IGR) to Salta (SLA) is not included in the program.

  • day 6:

    Salinas Grandes Salt Flat and Purmamarca

    Early in the morning, after breakfast, we begin a full day of travel through breathtaking landscapes. Our route runs parallel to the Train to the Clouds railway, following the dramatic Quebrada del Toro. We continue ascending until we reach an altitude of 4,080 meters above sea level, arriving at the highland town of San Antonio de los Cobres. Here, we’ll take a break for lunch and enjoy some of the typical regional dishes offered in the village. Back on the road, we follow the legendary Route 40 until we reach the stunning Salinas Grandes, the vast white salt flats located on the border between the provinces of Salta and Jujuy. From there, we begin our descent along the winding Cuesta de Lipán, a scenic mountain road where it's often possible to spot condors gliding overhead. Our journey ends in the charming town of Purmamarca, nestled at the base of the iconic Hill of Seven Colors, where we will spend the night. Lodging in Purmamarca — Double or Single Base Included Meals: Breakfast

  • day 7:

    Purmamarca

    Today is a free day to relax and explore Purmamarca at your own pace. We recommend starting the morning with a walk along the Paseo de los Colorados, a short and scenic trail that loops around the town and offers incredible views of multicolored hills and rock formations — a peaceful way to enjoy the unique landscape that surrounds Purmamarca. In the afternoon, for those wishing to venture further, we suggest an optional excursion to the Cerro Hornocal, also known as the Hill of Fourteen Colors, located near the city of Humahuaca. This spectacular geological formation, rising over 4,300 meters above sea level, displays vibrant stripes of mineral-rich sedimentary rock, creating one of the most stunning panoramic views in northern Argentina. Return to Purmamarca in the evening and enjoy the quiet charm of this Andean village. Lodging in Purmamarca - Double or Single Base Included meals: Breakfast

  • day 8:

    Quebrada de Humahuaca - Salta

    Departing from Purmamarca around mid-morning, we begin our journey south through the Quebrada de Humahuaca, a UNESCO World Heritage Site that combines breathtaking landscapes with deep-rooted Andean culture. We head north along the gorge, passing by Posta de Hornillos, and soon arrive at Tilcara, where you can take a short stroll through the town or visit the Pucará, a pre-Inca fortress offering panoramic views. Continuing along the route, we reach Huacalera, where we cross the Tropic of Capricorn and enjoy views of the multicolored “Pollera de la Colla” hill. We then stop at the village of Uquía to visit its historic church, famous for its Arcabuceros Angels, striking colonial paintings from the Cuzco School. Our northernmost point is Humahuaca, where we admire the Cathedral and the impressive Monument to Independence by sculptor Soto Avendaño. After some time for lunch and exploring, we begin our return journey. On the way back, we enjoy stunning views of the Painter’s Palette hill in Maimará, and continue descending through the gorge toward Salta, arriving in the late afternoon or early evening. Lodging in Salta — Double or Single Base Included Meals: Breakfast

  • day 9:

    Salta - San Pedro de Atacama

    At the indicated time, we will transfer to Salta’s bus station to board our bus to San Pedro de Atacama, crossing the Andes into Chile. Upon arrival, a local transfer will be waiting to take us to our accommodation. The rest of the day is at leisure to relax and begin discovering this unique desert town at your own pace. Lodging in San Pedro de Atacama — Double or Single Base Included Meals: Breakfast

  • day 10:

    Altiplanic Lagoons

    Today we will visit the stunning Miscanti and Miñiques Lagoons, located at over 4,000 meters above sea level. These high-altitude lagoons are known for their intense colors and breathtaking scenery, surrounded by snow-capped volcanoes and silence. On our way, we’ll stop at the charming village of Toconao, built entirely of volcanic stone and known for its traditional handicrafts and unique architecture. Another highlight of the day is the expansive Atacama Salt Flat (Salar de Atacama), stretching over 100 kilometers. Here, we will have the chance to observe native wildlife, including flamingos and other bird species that have adapted to one of the driest environments on Earth. The excursion offers a unique opportunity to discover some of the most striking and surreal landscapes in the Chilean Altiplano — a true highlight of the Atacama Desert. Lodging in San Pedro de Atacama - Double or Single Base Included Meals: Breakfast

  • day 11:

    Moon Valley

    We begin our journey under the watchful presence of the Tres Marías, iconic quartz and granite formations that stand at the entrance to the valley. Around these wind-carved sculptures, the hidden salt beneath the sand glistens like fragments of distant stars, and the overwhelming silence makes it feel as if we’ve been transported to the very satellite that lights our dreams each night. It’s a powerful, otherworldly sensation. From there, we continue into the heart of the mystical Moon Valley. Our next stop brings us to surreal salt caves, with ochre-hued rock walls and twisting natural paths. We move through this unexpected labyrinth with care, fully immersed in the textures and shadows, as darkness falls like a curtain, sharpening our senses. As we emerge once again into the open light, we exchange a knowing glance — one that says this is an experience worth repeating. To close the journey, we make our way to the Great Dune, arriving just in time to witness the sunset over the valley. The salt-covered mountains shift into a spectacular display of color, light, and shadow — a breathtaking moment that leaves a lasting impression. We return to San Pedro de Atacama filled with wonder, grateful for the chance to witness such a mystical landscape. Lodging in San Pedro de Atacama — Double or Single Base Included Meals: Breakfast

  • day 12:

    San Pedro de Atacama - Santiago de Chile

    At the indicated time, we will transfer to Calama Airport to board our flight to our next destination: Santiago de Chile. Upon arrival, a transfer will be waiting to take us to our accommodation. The rest of the day is at leisure to begin exploring the city or simply relax after the journey. Lodging in Santiago de Chile — Double or Single Base Included Meals: Breakfast ­ Please note that domestic Flight from Calama (CJC) to Santiago de Chile (SCL) is not included in the program.

  • day 13:

    Sightseeing in Santiago de Chile

    Today, we will explore the city center of Santiago de Chile, visiting some of its most iconic landmarks and neighborhoods. The tour begins in the historic heart of the city, where we’ll visit Plaza de Armas, the Cathedral, the Central Post Office, and the Municipality building. We’ll also stop by La Moneda Palace, the seat of the Chilean government, and stroll through some of the traditional neighborhoods that make up Santiago’s rich historical center. We continue to Santa Lucía Hill, originally called Huelén by the native peoples. This peaceful urban oasis offers a fascinating look into Chilean history and panoramic views of the city. Next, we head to Barrio Lastarria, one of the city's most charming districts, known for its vibrant cultural life, heritage architecture, and excellent gastronomy. The second part of the tour takes us to the eastern side of Santiago, home to the city’s financial district. Here we’ll see a different side of the capital, filled with modern buildings, gleaming glass skyscrapers, and contemporary sculptures by renowned Chilean architects. It’s easy to see why locals call this area “Sanhattan.” At the end of the tour, we return to our hotel. The rest of the day is at leisure to relax or continue exploring the city at your own pace. Lodging in Santiago de Chile - Double or Single Base Included Meals: Breakfast

  • day 14:

    Viña del Mar and Valparaiso

    No trip to Santiago is complete without visiting the colorful coastal cities of Valparaíso and Viña del Mar. We begin in Viña del Mar, known as the “Garden City” for its origins surrounded by green areas and for its beautifully preserved urban parks and gardens, all framed by the Pacific Ocean. The city stands out for its elegant architecture, impressive palaces, and the iconic Flower Clock, a favorite photo stop for travelers from around the world. During the visit, we’ll have the option to enjoy lunch at one of the many seaside restaurants, with an excellent variety of fresh seafood on offer. We’ll then drive along the coastal road, taking in sweeping ocean views on our way to Valparaíso, one of Chile’s most important ports. Declared a UNESCO World Heritage Site, Valparaíso captivates with its colorful hillside homes and unique geography, forming a natural amphitheater overlooking the sea. We’ll explore Cerro Alegre, a vibrant area known for its funiculars, street art, and stunning panoramic views. Our tour continues to Sotomayor Square, home to the Monument to the Heroes of Iquique, before arriving at the port. For those who wish, there is an optional boat ride around the bay — a great opportunity to admire the colorful hills of Valparaíso from the water. After the visit, we return to our hotel in Santiago de Chile. Lodging in Santiago de Chile - Double or Single Base Included Meals: Breakfast, Lunch

  • day 15:

    Santiago de Chile - Puerto Natales

    At the indicated time, we will transfer to Santiago de Chile’s airport to board our flight to Puerto Natales, gateway to Torres del Paine National Park and the heart of Chilean Patagonia. Upon arrival, a local transfer will be waiting to take us to our accommodation. The rest of the day is at leisure to relax and enjoy the peaceful atmosphere of this charming Patagonian town. Note: If your flight arrives in Punta Arenas instead, we can also arrange ground transportation from there to Puerto Natales. Lodging in Puerto Natales - Double or Single Base Included Meals: Breakfast ­ Please note that the domestic Flight from Santiago de Chile (SCL) to Puerto Natales (PNT) or Punta Arenas (PUQ) is not included in the program.

  • day 16:

    Torres del Paine National Park and Milodon Caves

    Today, we will enjoy a full-day excursion to the spectacular Torres del Paine National Park, one of the most stunning natural reserves in South America. We depart early from Puerto Natales, and on our way to the park, we stop to visit the Milodón Cave Natural Monument, an impressive cave where the remains of a prehistoric giant sloth (Milodón) were discovered over a century ago. A short walk will take us to the entrance of the cave, where we’ll learn about the fascinating paleontological history of the area. We then continue our journey through the Patagonian steppe, with vast landscapes and good chances to spot native wildlife such as guanacos, rheas, foxes, and condors. Once inside Torres del Paine National Park, we explore some of its most iconic viewpoints and natural highlights: Lago Sarmiento, Laguna Amarga, the Nordenskjöld Lake viewpoint, and the powerful Salto Grande waterfall. Depending on weather and park conditions, we may also reach the Lago Grey area, where you can enjoy a short walk to the lakeshore and see floating icebergs that have broken off from the Grey Glacier. A picnic lunch will be included during the excursion to enjoy surrounded by nature. After a day filled with unforgettable landscapes and photo opportunities, we return to Puerto Natales in the late afternoon. Lodging in Puerto Natales - Double or Single Base Included Meals: Breakfast, Box Lunch

  • day 17:

    Puerto Natales - El Calafate

    At the indicated time, we will leave Puerto Natales and begin our journey across the border into Argentina, heading towards the town of El Calafate, gateway to the majestic glaciers of Southern Patagonia. The drive offers scenic views of the Patagonian steppe, with its vast open landscapes and the occasional sighting of wildlife such as guanacos and condors. After completing border formalities, we continue through the Argentine side of Patagonia until we arrive in El Calafate. Upon arrival, transfer to the hotel and check-in. The rest of the day is at leisure to explore this charming town on your own, walk along the lakeshore, or visit the Glaciarium Ice Museum. Lodging in El Calafate - Double or Single Base Included Meals: Breakfast

  • day 18:

    Perito Moreno Glacier with Safari Nautico Boat Trip

    We depart in the morning from El Calafate and travel along the scenic Route 11, which borders the southern shore of Lago Argentino, offering beautiful views along the way. Once inside the national park, we’ll begin exploring the system of viewing balconies and walkways that offer multiple perspectives of the glacier. From these platforms, you’ll be able to admire the glacier’s towering ice wall — over 70 meters high — and, with some luck, witness dramatic ice calving as chunks of ice break off and crash into the lake below. As part of this experience, we’ll also enjoy the Safari Náutico, a boat navigation along the Rico Arm of Lago Argentino. The boat will take us up close to the southern face of the glacier, allowing us to appreciate its magnitude from the water. The views from the lake offer a truly unique and impressive perspective of the ice wall and its deep blue hues. After the visit, we return to El Calafate in the afternoon. The rest of the day is at leisure. Lodging in El Calafate - Double or Single Base Included Meals: Breakfast

  • day 19:

    El Calafate

    Today is a free day in El Calafate to relax, explore the town at your own pace, or choose from a variety of optional excursions. For those eager to continue discovering Patagonia’s natural beauty, we suggest a full-day trip to El Chaltén, a small mountain village located at the foot of the Fitz Roy Massif, about three hours away by road. Known as the trekking capital of Argentina, El Chaltén offers unforgettable views, scenic trails of varying difficulty, and a chance to immerse yourself in the heart of Los Glaciares National Park. This optional excursion includes round-trip transfers from El Calafate and offers time for short hikes, such as the trail to Mirador de Las Condes or Laguna Capri, depending on weather and interests. Alternatively, you may choose to explore El Calafate’s local attractions, such as the Glaciarium Ice Museum, a visit to a nearby Patagonian ranch (estancia), or simply enjoy a relaxed day by the shores of Lago Argentino. Lodging in El Calafate - Double or Single Base Included Meals: Breakfast

  • day 20:

    El Calafate - Ushuaia

    At the indicated time, we will transfer to El Calafate Airport to board our flight to Ushuaia, the southernmost city in the world, located on the shores of the Beagle Channel and surrounded by the Martial Mountain Range. Upon arrival, a local transfer will be waiting to take us to our accommodation. The rest of the day is at leisure to explore the city, walk along the waterfront, or visit some of the local museums and shops. Lodging in Ushuaia - Double or Single Base Included Meals: Breakfast Please note that the domestic flight from El Calafate (FTE) to Ushuaia (USH) is not included in the program

  • day 21:

    Tierra del Fuego National Park - Beagle Channel Boat Trip

    In the morning, we visit the stunning Tierra del Fuego National Park, located just a short drive from Ushuaia. Before entering the park, we board the historic End of the World Train, once used by prisoners of Ushuaia’s former penal colony. The train ride offers beautiful views of rivers, forests, and peat bogs, while sharing the history of the region. Once inside the park, we explore its main highlights, including Ensenada Bay, Laguna Verde, and Lapataia Bay, the southern terminus of National Route 3 and the Pan-American Highway. The landscapes blend Patagonian forest with the rugged coastline of the Beagle Channel, creating unforgettable scenery. In the afternoon, we head to the port to embark on a navigation of the Beagle Channel. We sail around Bird Island and Sea Lion Island, observing colonies of cormorants, sea lions, and other marine wildlife in their natural habitat. One of the highlights of this excursion is the disembarkation on Bridges Island, where we take a guided walk to discover the native flora, archaeological remains of the Yámana people (such as ancient shell middens), and panoramic views of the channel and the surrounding mountains. The navigation continues toward the Les Eclaireurs Lighthouse, often referred to as the "Lighthouse at the End of the World," before returning to the port of Ushuaia. After this unforgettable day in nature and history, we return to our hotel. Evening at leisure. Lodging in Ushuaia - Double or Single Base Included Meals: Breakfast

  • day 22:

    Departure Ushuaia

    At the indicated time, we transfer to Ushuaia airport, where our services end. Meals: Breakfast

  • Duration : 22 days
  • Price : From €5,790 per person
  • Destinations: Argentina